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. 2008 Jan 21;205(1):133–141. doi: 10.1084/jem.20070962

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Copyright © 2008, The Rockefeller University Press

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Figure 1. — Joint-specific up-regulation of B. burgdorferi bmpA and bmpB in infected mice. The relative expression levels of bmpA (black bar) and bmpB (gray bar) are represented as copies of bmp transcript per 1,000 copies of flaB transcript. Total RNA was isolated from multiple tissues of B. burgdorferi–infected mice (10 mice/group) and converted to cDNA for measuring bmp transcripts using qPCR 12 and 15 d after challenge. Bars represent the mean ± the SEM from three independent experiments. The transcript levels in joints were significantly higher than those in skin, heart, or bladder tissue. n = 3. P < 0.01–0.001.