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. Author manuscript; available in PMC: 2008 Feb 20.
Published in final edited form as: Stroke. 2004 Nov 29;36(1):113–117. doi: 10.1161/01.STR.0000149949.92854.45

Figure 2. Diameter changes measured in response to flow (shear stress) in isolated tail caudal arteries.

Figure 2

A- Changes in diameter in response to stepwise increases in intraluminal flow were determined in caudal arteries submitted to a pressure of 75mmHg and preconstricted with phenylephrine. Flow-mediated dilation is expressed as percentage dilation of active tone by flow.

B- Flow-induced dilation (in μm change in diameter) is expressed as a function of shear stress. Caudal arteries were isolated from wild-type (n=12) and transgenic mice (n=9 and n=10, lines TgMa and TgVe respectively).

*P <0.001; two-factor ANOVA, transgenic versus wild-type mice.