Figure 3.
Effect of lipid composition on the fluorescence properties of A2E. The change in the fluorescence emission maximum (A) and the fluorescence intensity (B) upon addition of A2E to the model membranes of DOPC, DOPE, DOPS, DOPC:DOPE (1:1), DOPC:DOPE:DOPS (0.45:0.45:0.1), and DOPC:DOPE:DOPS (0.4:0.4:0.2) was plotted against the A2E concentration. In all the cases, lipid concentration was 500 μM. Different amounts of A2E solution were injected to the aqueous dispersions to reach a particular concentration of A2E. The excitation wavelength was 400 nm and all the measurements were done at 25°C.