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. 2004 May;123(5):555–571. doi: 10.1085/jgp.200308876

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Copyright © 2004, The Rockefeller University Press

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Figure 8. — The “IQ-AA” mutant, in which Ca²⁺/calmodulin does not accelerate inactivation of Ca²⁺ current, was affected in the same manner as the wild-type channel. Both ionic and OFF gating currents were reduced by the Ca²⁺ load. Experimental protocol was as in Fig. 3 B.