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. 2004 Jun;123(6):709–727. doi: 10.1085/jgp.200308983

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Copyright © 2004, The Rockefeller University Press

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Figure 13. — Cooling traps Gd⁺³ in the membrane. Representative effects of a temperature change on the actions of Gd⁺³. A decrease of bath temperature to 4°C altered the inhibitory time course of Gd⁺³. This temperature change also rendered Gd⁺³ completely irreversible by presumably locking its interaction with the plasma membrane. See text for additional details. Similar effects were also observed at 10°C and with CPZ (not depicted).