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. 2004 Jun;123(6):709–727. doi: 10.1085/jgp.200308983

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Copyright © 2004, The Rockefeller University Press

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Figure 3. — Effects of temperature on control oocytes. (A and B) Representative effects on the capacitance and conductance. Cooling caused a small stimulation of C_m and a rapid decrease of g_m. The decrease of conductance was monotonic, in contrast to that observed in hENaC-expressing oocytes. (C and D) Summary of the changes induced by temperature. (C) The decrease of conductance could be fit with a single exponential function with a constant of 6.2°C. (D) The increase of C_m was ∼10% at 15°C, and was similar to that observed with ENaC (Fig. 2). This small increase is unlikely related to trafficking, but rather to the effects of temperature on the membrane dielectric coefficient (see text). Data are normalized to the values at 25°C or control which averaged 2.6 ± 0.5 mS and 0.218 ± 0.012 mF for g _m and C_m, respectively. n = 6.