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. 2004 Jun;123(6):709–727. doi: 10.1085/jgp.200308983

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Copyright © 2004, The Rockefeller University Press

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Figure 6. — Summary of effects of temperature on voltage activation. Experiments were performed in oocytes bathed in ND94. (A) A large increase of t is observed with decreasing temperature leading to ∼5-fold increase at 10°C. (B) A biphasic stimulation of the magnitude of voltage activation (ΔI_V) is observed with a T_max in the range of that calculated for g _Na (see Fig. 2). (C) A similar biphasic stimulation is also observed with the initial current at −100 mV (I₋₁₀₀), and (D) with the ratio of ΔI_V to I₋₁₀₀. Values at 4°C were eliminated as the time constants were >1,500 ms and could not be accurately fit from the acquired data points. n = 7.