Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2004 Jun;123(6):697–708. doi: 10.1085/jgp.200409042

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2004, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — ACh concentration-response curves of α3β4 nAChR expressed in oocytes from monomer or tandem constructs are indistinguishable. (A) Traces are inward currents recorded at a holding potential of −70 mV in response to bath-applied ACh. (B) ACh concentration-response curves from experiments such as the ones shown in A, performed in oocytes injected with either α3 and β4 monomer cRNAs (filled circles, n = 9) or β4_α3 tandem together with β4 monomer cRNAs (open circles, n = 4). Full sets of peak responses to ACh from each oocyte were fitted with the Hill equation and normalised to the fitted maximum response before pooling (see materials and methods). The curves shown are the results of fitting the pooled data.