TABLE II.
β4_α3 Tandem Expressed Together with Monomeric Subunits
| β4_α3 + | I max a | cRNA | n oocyte | n batch |
|---|---|---|---|---|
| nA | ng | |||
| — | 0 ± 0 | 2 | 6 | 2 |
| α2 | 13 ± 7 | 2:0.5 | 6 | 2 |
| α3 | 0 ± 0 | 2:0.5 | 6 | 2 |
| α4 | 0 ± 0 | 2:0.5 | 6 | 2 |
| α5 | 7 ± 4 | 2:0.5 | 5 | 2 |
| α6 | 0 ± 0 | 2:0.5 | 5 | 2 |
| β2 | 5 ± 5 | 2:0.5 | 6 | 2 |
| β3 | 0 ± 0 | 2:0.5 | 6 | 2 |
| β4 | 2,587 ± 702 | 2:0.5 | 10 | 3 |
The maximum current measured for the β4_α3 tandem constructs expressed in Xenopus oocytes alone (—) or in combination with any of the nicotinic monomers that can form heteromeric receptors.
a
Measured at 1 mM ACh, mean ± SEM.