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. 2004 Jun;123(6):643–656. doi: 10.1085/jgp.200409089

Figure 2.

Figure 2.

The lever arm movement of the light chain domain. Reconstructions of the actin–myosin complex at the beginning and end of the power stroke. (A) The “beginning” of the power stroke, based on the truncated S1–ADP.vanadate coordinates (PDB-1VOM). The missing lever arm has been restored using the chicken S1 coordinates (PDB-MYS) with an appropriate rotation. The break in the chain at the beginning of the lever arm marks the extent of the fragment of S1 used in the crystal structure analysis. (B) The “end” state, or rigor complex. Note that the end of the lever arm moves ∼12 nm between the two states. Regions of myosin are colored as in Fig. 1, with the exception that the colors of the light chains have been switched. Diagram prepared with GRASP (Nicholls et al., 1991). Reproduced with permission from Holmes (1997).