Table 3.
The estimated KCNE1 haplotype frequencies in the group with the shortest and the group with the longest QTc intervals and odds ratios for the haplotypes.
| rs2236609 | rs1805127 (G38S) | Shortest QTc (N=392 alleles) | Longest QTc (N=396 alleles) | OR (95% CI)‡ | |
|---|---|---|---|---|---|
| H1 | C | G | 0.517 | 0.468 | ref |
| H2 | T | G | 0.119 | 0.152 | 1.30 (0.86–1.97), P=0.21 |
| H3 | C | A | 0.056 | 0.111 | 1.97 (1.11–3.48), P=0.02 |
| H4 | T | A | 0.308 | 0.269 | 0.97 (0.69–1.37), P=0.87 |
P= 0.081 for the global association.
Odds ratios with 95% confidence intervals (95% CI) were calculated with reference to the most common haplotype H1