Table 1.
Risk factors for PTLD and HCV prevalence by demographic group among 210 763 solid organ transplant recipients
| Patients with PTLD, no. | PTLD HR (95% CI)* | HCV prevalence, %† | |
|---|---|---|---|
| Total | 1630 | — | 11.3 |
| Sex | |||
| Female | 606 | 1.00 (referent) | 8.2 |
| Male | 1024 | 1.08 (0.98-1.19) | 13.3 |
| Age, y | |||
| 0-20 | 479 | 6.80 (5.45-8.48) | 1.6 |
| 21-30 | 125 | 1.77 (1.36-2.31) | 2.6 |
| 31-35 | 76 | 1.30 (0.96-1.76) | 4.7 |
| 36-40 | 94 | 1.25 (0.94-1.67) | 10.0 |
| 41-45 | 94 | 1.00 (referent) | 17.8 |
| 46-50 | 182 | 1.65 (1.29-2.12) | 20.6 |
| 51-55 | 181 | 1.69 (1.31-2.16) | 16.2 |
| 56-60 | 181 | 1.93 (1.50-2.47) | 10.2 |
| 61-65 | 144 | 2.10 (1.62-2.72) | 9.0 |
| > 65 | 74 | 1.79 (1.32-2.43) | 8.2 |
| Race | |||
| White, non-Hispanic | 1294 | 1.00 (referent) | 10.9 |
| Black, non-Hispanic | 145 | 0.46 (0.39-0.55) | 12.2 |
| Hispanic | 124 | 0.63 (0.52-0.76) | 13.3 |
| Asian | 46 | 0.63 (0.47-0.85) | 9.0 |
| Other/unknown | 21 | 1.09 (0.71-1.67) | 8.2 |
| Education | |||
| 0 to 8 y | 34 | 1.00 (referent) | 11.5 |
| 9 to 12 y | 333 | 1.24 (0.87-1.76) | 13.6 |
| Some college | 186 | 1.28 (0.89-1.85) | 12.2 |
| College graduate | 215 | 1.64 (1.14-2.35) | 9.0 |
| Unknown | 365 | 1.18 (0.83-1.67) | 12.8 |
| Recipients younger than 22 y | 497 | 4.99 (3.52-7.06) | 1.6 |
| Organ transplant | |||
| Heart and/or lung | 513 | 2.95 (2.63-3.31) | 1.8 |
| Kidney and/or pancreas | 698 | 1.00 (referent) | 4.9 |
| Liver | 382 | 1.73 (1.53-1.96) | 40.2 |
| Other | 37 | 4.13 (2.97-5.75) | 26.2 |
— indicates not applicable.
*
PTLD HRs are unadjusted.
†
HCV prevalence among 182 121 recipients with known HCV status at the time of transplantation; HCV status was unknown for an additional 28 642 (13.6%) of all recipients.