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. 2007 Nov 23;116(2):231–237. doi: 10.1289/ehp.10623

Table 3.

Incidence rate ratios for cancer in association with arsenic exposure.

Adjusted analysis
Further adjustment for area of enrollment
Cancer No. of cases IRR 95% CI p-Value IRR 95% CI p-Value
Time-weighted average exposure (μg/L)
 Colorectala 441 0.97 0.90–1.05 0.49 0.93 0.84–1.04 0.21
 Liverb 35 1.05 0.88–1.25 0.57 0.97 0.72–1.29 0.81
 Lungc 402 0.99 0.92–1.07 0.78 0.99 0.90–1.08 0.76
 Breastd 766 1.03 0.99–1.08 0.20 1.05 1.01–1.10 0.02
 Prostatee 332 1.03 0.97–1.09 0.41 1.03 0.96–1.10 0.45
 Kidneyf 53 0.89 0.65–1.22 0.46 0.88 0.58–1.35 0.57
 Bladderg 214 1.01 0.93–1.11 0.75 1.00 0.91–1.11 0.93
 Melanoma skinh 147 0.89 0.73–1.07 0.20 0.80 0.59–1.08 0.14
 Non-melanoma skini 1,010 0.88 0.81–0.94 0.0004 0.99 0.94–1.06 0.85
Cumulated exposure (5 mg)
 Colorectala 441 0.98 0.96–1.01 0.28 0.97 0.93–1.01 0.10
 Liverb 35 0.99 0.89–1.10 0.79 0.89 0.73–1.08 0.24
 Lungc 402 1.0 0.98–1.02 0.80 1.00 0.98–1.03 0.75
 Breastd 766 1.0 0.99–1.02 0.61 1.01 0.99–1.03 0.21
 Prostatee 332 1.0 0.99–1.03 0.44 1.01 0.99–1.03 0.44
 Kidneyf 53 0.94 0.84–1.06 0.33 0.94 0.81–1.09 0.38
 Bladderg 214 1.0 0.98–1.04 0.55 1.01 0.98–1.04 0.69
 Melanoma skinh 147 0.97 0.92–1.03 0.35 0.96 0.89–1.04 0.32
 Non-melanoma skini 1,010 0.95 0.92–0.97 < 0.0001 0.99 0.97–1.01 0.35
a

Adjusted for smoking status, smoking duration, smoking intensity, education, body mass index (BMI), alcohol status, daily intake of alcohol, hormone replacement therapy (HRT) status, years of HRT use, occupation, daily intake of: red meat, dietary fibres, and fruits/vegetables.

b

Adjusted for smoking status, smoking duration, smoking intensity, education, alcohol status, daily intake of alcohol, occupation.

c

Adjusted for smoking status, smoking duration, smoking intensity, education, occupation, daily intake of fruits/vegetables.

d

Adjusted for HRT status, years of HRT use, no. of births, age at first birth, education, alcohol status, daily intake of alcohol, daily intake of fruits/vegetables, BMI, occupation.

e

Adjusted for education, BMI, daily intake of: fruits/vegetables and fat.

f

Adjusted for smoking status, smoking duration, smoking intensity, education, BMI, occupation.

g

Adjusted for smoking status, smoking duration, smoking intensity, education, occupation.

h

Adjusted for education, skin reaction to sun, suntanned during summer.

i

Adjusted for education, skin reaction to sun, suntanned during summer, occupation.