Table 1.
Cell lines | 5-aza-CdR (μM) | Rates of APRT- colony formation (10-7)a | P value vs 0 μM | P value vs 1 μM |
---|---|---|---|---|
GSAA5 | 0 | 48 ± 7 | 0.7 | |
0.5 | 36 ± 2 | 0.15 | 0.4 | |
1 | 62 ± 24 | 0.7 | ||
AT3-2 | 0 | 5.0 ± 0.5 | 0.8 | |
0.5 | 3.5 ± 0.2 | 0.06 | 0.6 | |
1 | 4.6 ± 2 | 0.8 |
Results represent at least three independent experiments. In each experiment, three to four different plates were treated in parallel and the mean rates for each experiment were averaged. The standard error is shown.