Table 2.
Summary of the Phylogenetic Analysis of Gene Families
| Family Name | Hsa2 | Hsa7/3* | Hsa12 | Hsa17 | Consistency with HOX Phylogeny | Topology |
| ERBB | ERBB4 | EGFR | ERBB3 | ERBB2 | - | (((17, 7)2)12) 97,98 |
| Collagen | COL3A1 COL5A2 |
COL1A2 | COL2A1 | COL1A1 | - | ((((12,17)7)2)2) 93,92,83 |
| IGFBP | IGFBP2 IGFBP5 |
IGFBP1 IGFBP3 |
IGFBP6 | IGFBP4 | - | ((17, 7)2) ((7, 2)12)99,91 |
| INTB | ITGB6 | ITGB5* | ITGB7 | ITGB3 | - | (((3, 17)2)12) 98,99 |
| MYL | MYL1 | - | MYL6 | MYL4 | - | ((17, 2)12) 87 |
| SP | Sp3 | Sp4 | Sp1 | Sp2 | Yes | (((12,2)7)17) 98,89 |
| ZNFN1A | ZNFN1A2 | ZNFN1A1 | ZNFN1A4 | ZNFN1A3 | - | (((7,17)2)12) 94,90 |
| INHB | INHBB | INHBA | INHBC INHBE |
- | - | ((7,2)12) 93 |
| SLC4A | SLC4A3 | SLC4A2 | - | SLC4A1 | - | ((7,2)17) 85 |
| GLI | GLI2 | GLI3 | GLI1 | - | - | ((7,2)12) 99 |
| HH | IHH | SHH | DHH | - | ((7,2)12) 97 |
For each gene family the chromosomal location and topologies (in the Newick format) of those genes are given, which arose through duplications after the invertebrates-vertebrates split and before the tetrapods-fishes divergence. The percentage bootstrap support of the internal branches is given below each relevant topology.