Table 1.
Host polymorphism and parasitological data for 555 children from the Amele region, Papua New Guinea
| P. falciparum Prevalencea | |||||
| Host Polymorphism | Negative | Positive | Positive | ||
| Frequency | Both surveys | One survey | Both surveys | Pb | |
| n (%) | n (%) | n (%) | n(%) | ||
| α+-Thalassaemia | |||||
| (αα/αα) | 39 (7.1) | 15 (38.5) | 19 (48.7) | 5 (12.8) | . |
| (-α/αα) | 205 (36.9) | 75 (37.1) | 94 (46.5) | 33 (16.3) | 0.72 |
| (-α/-α) | 311(56.0) | 125 (41.7) | 120 (40.0) | 55 (18.3) | 0.99 |
| CR1c | |||||
| HH | 29 (5.4) | 14 (48.3) | 12 (41.4) | 3 (10.3) | . |
| HL | 188 (35.5) | 70 (38.0) | 78 (42.4) | 36 (19.6) | 0.07 |
| LL | 313 (59.1) | 121 (39.9) | 133 (43.9) | 49 (16.2) | 0.11 |
| ABOc | |||||
| O | 180 (32.6) | 69 (39.4) | 66 (37.7) | 40 (22.9) | . |
| non-O | 372 (67.4) | 145 (39.9) | 165 (45.5) | 53 (14.6) | 0.09 |
| A | 178 (32.2) | 62 (35.6) | 80 (46.0) | 32 (18.4) | 0.83 |
| B | 138 (25.0) | 62 (46.6) | 58 (43.6) | 13 (9.8) | 0.005 |
| AB | 56 (10.1) | 21 (37.5) | 27 (48.2) | 8 (14.3) | 0.27 |
| SAOc | |||||
| Normal | 506 (91.2) | 200 (40.4) | 211 (42.6) | 84 (17.0) | . |
| SAO | 49 (8.8) | 15 (32.6) | 22 (47.8) | 9 (19.6) | 0.29 |
| G6PDc | |||||
| Normal | 477 (89.7) | 182 (39.1) | 199 (42.7) | 85 (18.2) | . |
| Intermediate | 20 (3.8) | 8 (44.4) | 6 (33.3) | 4 (22.2) | 0.76 |
| Deficient | 35 (6.6) | 16 (45.7) | 16 (45.7) | 3 (8.6) | 0.36 |
a Missing data: 1999, n = 1; 2000, n = 21.
b Differences in frequency of positive slides were assessed using ordinal regression with adjustments for age.
c Abbreviations: CR1, Complement receptor 1; SAO, Southeast Asian Ovalocytosis; G6PD, Glucose-6-phosphate dehydrogenase deficiency. With the exception of SAO, these variables contain missing values.