Table 1.

MS patient characteristics

MS Males					MS Females
			HLA Class II c					HLA Class II
Study ID	DDa	Ageb	DRB1	DQB1	Study ID	DD	Age	DRB1	DQB1
18	1.5	46	-d	-	4	0.4	53	-	-
29	4.4	48	-	-	5	4.3	40	-	-
50	4.0	50	-	-	13	0.4	39	1,15*	5,6
74	0.2	30	12,15	3,6	15	1.5	50	-	-
87	0	47	3,7	3,2	17	9	43	-	-
103	2.9	48	7	3	19	0.3	36	-	-
106	0.4	46	4,15	3,6	20	1.3	37	-	-
117	3.1	34	1,15	5,6	31	0.3	37	-	-
122	3.5	29	9,11	3	37	7	46	8,12	3,4
133	0.08	40	7,15	2,6	45	1.8	28	1,13	5,6
139	0.1	33	8,15	4,6	46	.3	42	-	-
140	0.07	35	4,15	3,6*	48	.3	31	15,14	5,6
141	0.1	42	3,8	2,3	52	1.1	29	10,13	5,3
143	0.1	29	1,15	5,6	60	3.3	40	-	-
145	0.3	45	1*,15	3,6	76	2.5	46	4,16	3,5
147	0.08	47	7,15	3,6	78	1.0	33	3,15	2,6
160	0	33	-	-	81	0.04	23	1,15	5,6
174		46	-	-	83	1.2	46	13,14	5,6*
178	0.1	19	1,4	5,3	99	0.1	34	1,15	5,6
179	2.6	60	11	3	105	0.9	50	4,14	3,5
184	0	57	-	-	107	0.1	41	7,15	2,6
185	0	40	-	-	110	12.9	39	13,15	3,6
					112	0.01	44	3,15	2,6*
					113	0.09	33	13,14	5,6*
					119	0.2	43	10,15	5,6
					123	9.5	52	15*	6
					126	1.5	24	11,13	3,6
					127	0.2	33	4,15	3,6
					130	2.7	45	4,15	3,6
					131	3.3	35	7,15	3,6
					134	0.1	30	3,8	4,6
					135	0.2	34	7,11	2,3
					138	0.6	42	-	-
					146	0.1	23	1*,11	3
					148	12.2	41	11,15	3,6
					149	0.5	33	8,15	3,6
					151	0.1	31	13	3,6*
					153	5.4	30	7,11	2,3

^aDD is disease duration in years.

^bAverage ages: MS males, 41.1 ± 9.9 yrs, MS females, 37.8 ± 7.9 yrs.

^cHLA Class II lists both alleles separated by a comma (homozygous individuals have only one number). Four-digit molecular HLA typing has been simplified to 2 digits (e.g. *1501 is shortened to 15; *1301 is shortened to 13; *0401 is 4; *0101 is 1; *0301 is 3). Numbers followed by “*” are allelic variants: 1* is *0103 (not the same as *0101); 15* is 1503, an allelic variation that is rare in Caucasians; 6* is *0602 but ambiguities exist with 0619 and 0620. Representation of HLA types: DR15: MS M 53%; MS F 43%; DR4: MS M 20%; MS F 14%; DR3: MS M 13%; MS F 11%.

^dDashes are data that were not tested or unavailable.