. Author manuscript; available in PMC: 2009 Jan 1.

Published in final edited form as: J Neuroimmunol. 2007 Nov 26;193(1-2):161–169. doi: 10.1016/j.jneuroim.2007.10.010

Table 4.

IL-5 significant gender responses are male skewed

	Male vs. Female				By DX and Sex
Antigen	Sex	Avg^a	SE^a	P value^b	Dx,Sex^c	Avg^a	SE^a
MOG 1−22	F	0.59	0.22		C M	1.15**^d	0.50
	M	1.56	0.57	<0.0001	C F	0.32	0.09
					MS M	2.26***	1.32
					MS F	0.91	0.46
MOG 34−56	F	0.28	0.07		C M	0.39	0.14
	M	0.83	0.33	0.0069	C F	0.22	0.07
					MS M	1.58***	0.85
					MS F	0.34	0.13
MBP 87−106	F	0.51	0.14		C M	1.33	0.64
	M	1.48	0.65	0.0094	C F	0.63	0.12
					MS M	1.74*	0.38
					MS F	0.37	0.14
PLP 40−60	F	0.29	0.07		C M	0.85*	0.49
	M	1.29	0.48	0.0008	C F	0.32	0.10
					MS M	2.05**	1.01
					MS F	0.26	0.09
PLP 89−106	F	0.46	0.19		C M	1.21	0.81
	M	1.33	0.59	0.037	C F	0.32	0.11
					MS M	1.53	0.79
					MS F	0.63	0.40
PLP 103−120	F	0.41	0.09		C M	1.24*	0.64
	M	1.17	0.43	0.0064	C F	0.39	0.12
					MS M	1.05	0.38
					MS F	0.43	0.14
PLP 139−158	F	0.34	0.09		C M	1.15	0.70
	M	1.21	0.50	0.0023	C F	0.32	0.11
					MS M	1.32*	0.68
					MS F	0.37	0.15
PLP 195−206	F	0.38	0.09		C M	1.76	0.76
	M	1.65	0.53	0.0001	C F	0.54	0.14
					MS M	1.47***	0.65
					MS F	0.20	0.08
MBP	F	2.1	1.64	0.0106	C M	0.94	0.29
	M	2.1	0.78		C F	3.46	3.04
					MS M	4.16***	2.04
					MS F	0.51	0.18

Mean and standard error (SE) of IL-5 secreting cells. Bold numbers highlight where MS Males (MS M, right side) showed the highest IL-5 responses of any disease (DX) or sex combination.

Negative binomial regression P values showing significant difference between all male vs. all female responses.

DX, Sex: C M, control males (n=33); C F, control females (n=41); MS M, MS males (n= 19); MS F, MS females (n=35).

Asterisks represent P values in pairwise comparisons where MS M were significantly greater than MS F (*** p≤0.001, **p≤0.01, *p≤0.05) or C M greater than C F.