TABLE 1.

Hepatic mRNA levels of GST-π and Dnmt1, 3a, and 3b in Fisher rats fed control or FMD diet for 9, 18, or 36 wk¹

					2-Way ANOVA
Gene	Diet	9 wk	18 wk	6 wk	Diet	Age	Diet × age
copy number/105 copies of 18S rRNA
GST-π2	Control	50.74 ± 5.32	53.08 ± 6.26	49.26 ± 4.64	<0.001	0.169	0.38
	FMD	136.97 ± 16.32*	152.36 ± 7.44*	96.52 ± 51.01*
Dnmt1	Control	14.13 ± 1.56a	10.16 ± 3.08b	7.19 ± 1.48c	<0.001	<0.001	0.004
	FMD	32.06 ± 6.68*a	16.34 ± 4.18*b	11.61 ± 1.86*c
Dnmt3a	Control	1.37 ± 0.31	0.83 ± 0.58	1.00 ± 0.31	<0.001	0.004	0.06
	FMD	3.86 ± 0.88*	2.62 ± 0.76*	1.95 ± 0.59*
Dnmt3b	Control	4.56 ± 2.76	5.22 ± 3.64	4.47 ± 3.07	0.047	0.056	0.12
	FMD	4.21 ± 2.17	12.23 ± 5.52	6.78 ± 2.30

¹Values are means ± SD, n = 4. Means in a row without a common letter differ, P < 0.01.

^*Different from the control group at that time, P < 0.01.

²GST-π, glutathione S-transferase π.