Table 3.
Unadjusted and adjusted probability of spontaneous abortion among pregnancies occurring after July 1, 1973.
Unadjusted GEEa n=1344 |
Adjusted GEE a n=1344 |
Adjusted Logistic b n=529 |
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---|---|---|---|---|---|---|
OR | 95% CI | OR | 95% CI | OR | 95% CI | |
PBB (ppb)c | ||||||
< 1 | Ref | Ref | Ref | |||
1–2.9 | 1.07 | 0.69-1.66 | 1.05 | 0.67-1.63 | 0.51 | 0.24-1.11 |
> 2.9 | 0.69 | 0.45-1.07 | 0.73 | 0.47-1.13 | 0.67 | 0.33-1.33 |
PCB (ppb) | ||||||
≤ 5 | Ref | Ref | Ref | |||
> 5 – 6.5 | 1.06 | 0.68-1.64 | 0.97 | 0.62-1.52 | 1.14 | 0.57-2.26 |
> 6.5 | 0.88 | 0.57-1.36 | 0.91 | 0.59-1.41 | 1.15 | 0.56-2.36 |
Not measured | 0.50 | 0.20-1.27 | 0.48 | 0.19-1.26 | 0.76 | 0.21-2.78 |
Maternal age at conception (years) |
||||||
< 20 | Ref | Ref | Ref | |||
20 – 29 | 0.96 | 0.56-1.64 | 0.94 | 0.55-1.61 | 0.60 | 0.30-1.21 |
30 - 34 | 1.13 | 0.62-2.06 | 1.07 | 0.57-2.01 | 1.22 | 0.45-3.31 |
≥ 35 | 2.76 | 1.22-6.27 | 2.46 | 1.10-5.49 | 2.11 | 0.70-6.36 |
Age at Menarche | ||||||
≤ 11 | Ref | Ref | Ref | |||
12- 13 | 0.52 | 0.34-0.80 | 0.58 | 0.38-0.89 | 0.30 | 0.16-0.57 |
≥ 14 | 0.53 | 0.32-0.87 | 0.55 | 0.34-0.91 | 0.37 | 0.17-0.81 |
Prior Infertilityd | ||||||
No | Ref | Ref | Ref | |||
Yes | 1.68 | 1.11-2.54 | 1.52 | 0.98-2.38 | 1.74 | 0.92-3.30 |
Abbreviations: GEE, generalized estimating equation, OR, odds ratio; CI, confidence interval; PBB, polybrominated biphenyls; PCB polychlorinated biphenyls; pbb, parts per billion.
Generalized estimating equations were used to account for the dependency between pregnancies of the same woman. Adjusts for all covariates in table.
The adjusted Logistic Model includes only the first pregnancy after July 1, 1973 for each woman and controls for all of the covariates listed in the table.
PBB at the time of conception as determined by the decay model.
Prior to index pregnancy