TABLE 1.
Allele and nucleotide or genotype | Frequency among subjects (mean ± SD)a
|
Pb | ORc | |
---|---|---|---|---|
Patients | Controls | |||
TNF-α −308 G/A | ||||
G | 0.85 ± 0.03 | 0.88 ± 0.03 | 0.775 | 0.822 |
A | 0.15 ± 0.03 | 0.12 ± 0.03 | 0.386 | 1.352 |
G/G | 0.73 ± 0.03 | 0.79 ± 0.03 | 0.491 | 0.733 |
G/A | 0.23 ± 0.02 | 0.19 ± 0.02 | 0.546 | 1.344 |
A/A | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.866 | 1.303 |
LT-α +249 A/G | ||||
A | 0.54 ± 0.04 | 0.69 ± 0.04 | 0.018 | 0.373 |
G | 0.46 ± 0.04 | 0.31 ± 0.04 | 0.042 | 1.872 |
A/A | 0.32 ± 0.03 | 0.47 ± 0.03 | 0.061 | 0.530 |
A/G | 0.45 ± 0.03 | 0.43 ± 0.03 | 0.966 | 1.065 |
G/G | 0.23 ± 0.02 | 0.10 ± 0.01 | 0.030 | 2.791 |
Subjects comprised 228 T1DM patients and 240 healthy subjects.
Pearson's chi-square test.
Calculated according to the Woolf method.
Data in bold indicate statistically significant differences.