TABLE 3.
Absolute categorical agreement and error rates when the fluconazole result was used to predict the posaconazole susceptibility of Candida spp.
| Species | No. of isolates tested | % Agreement | % VME | % ME | % M |
|---|---|---|---|---|---|
| All Candida | 10,807 | 91.1 (93.7)a | 0.1 (0.1)a | 1.2 (0.2)a | 7.6 (6.0)a |
| C. albicans | 5,827 | 99.3 | 0.0 | 0.1 | 0.6 |
| C. parapsilosis | 1,542 | 96.2 | 0.0 | 0.6 | 3.2 |
| C. glabrata | 1,517 | 66.2 (86.0)b | 0.1 (1.6)b | 0.3 (0.3)b | 33.4 (12.1)b |
| C. tropicalis | 1,198 | 99.2 | 0.0 | 0.1 | 0.7 |
| C. krusei | 305 | 2.3 | 0.0 | 33.1 | 64.6 |
| C. guilliermondii | 138 | 89.9 (97.1)b | 0.0 | 0.0 | 10.1 (2.9)b |
| C. lusitaniae | 133 | 97.7 | 0.0 | 1.5 | 0.8 |
| C. kefyr | 51 | 100 | 0.0 | 0.0 | 0.0 |
| C. pelliculosa | 31 | 58.1 | 6.4 | 0.0 | 35.5 |
| C. famata | 19 | 89.5 (94.7)b | 0.0 | 0.0 | 10.5 (5.3)b |
| C. rugosa | 13 | 61.5 (100)b | 0.0 | 0.0 | 38.5 (0.0)b |
| C. dubliniensis | 12 | 100 | 0.0 | 0.0 | 0.0 |
| C. lipolytica | 12 | 100 | 0.0 | 0.0 | 0.0 |
| C. zeylanoides | 8 | 87.5 | 0.0 | 0.0 | 12.5 |
a
The value in parentheses is based on the results for all of the Candida species minus C. krusei (10,502 isolates).
b
The value in parenthesis was obtained by using the following categories for fluconazole: susceptible, MIC of ≤32 μg/ml (S and SDD combined); resistant, MIC of ≥64 μg/ml.