TABLE 3.
Comparison of the MALDI-TOF MS results with reference PCR-based methods
| Virus analysis | Total | No. of samplesa
|
Concordance (%) | κ | |||
|---|---|---|---|---|---|---|---|
| −Ref/−MS | +Ref/+MS | −Ref/+MS | +Ref/−MS | ||||
| HSV-1 | 435 | 325 | 98 | 2 | 10 | 97.2 | 0.92 |
| HSV-2 | 435 | 322 | 104 | 3 | 6 | 97.9 | 0.94 |
| CMV | 129 | 63 | 54 | 2 | 10 | 90.7 | 0.81 |
| VZV | 164 | 79 | 74 | 3 | 8 | 93.3 | 0.87 |
| EBV | 164 | 94 | 58 | 0 | 12 | 92.7 | 0.85 |
| HHV8 | 22 | 10 | 9 | 0 | 3 | 86.4 | 0.73 |
| Total | 1,349 | 893 | 397 | 10 | 49 | 95.6 | 0.90 |
Ref, reference results; MS, MALDI-TOF MS results.