TABLE 4.

MALDI-TOF MS results in relation to the original clinical diagnostic request

Virus analysis requested (no. of samples)	No. of samples determined to be positive by MALDI-TOF MS analysis for:
	HSV-1	HSV-2	CMV	VZV	EBVA	EBVB	HHV8	HHV6	HHV7	Two HHVsa	Three HHVsa	Four HHVsa
HSV (435)	100	107	0	20b	11	1	0	5	21	16c	1d	1e
CMV (129)	0	0	56	0	4	1	0	2	3	6f
VZV (164)	14	16g	0	77	0	0	0	4	0	5h
EBV (164)	0	0	0	0	56	2	0	2	0	1i
HHV8j (22)	0	0	1	0	1	0	9	0	0	2k

^aEither two, three, or four herpesviruses, as indicated in the respective footnotes, were detected in the same samples; these values were also included in the column for respective virus.

^bFourteen samples were also submitted for VZV analysis.

^cThree EBVA and HHV7, one VZV and HHV6, two EBVA and HSV-1, one EBVA and HSV-2, one HSV-1 and HSV-2, two HHV6 and HSV-1, and six HHV7 and HSV-1.

^dHSV-1, HHV6, and HHV7.

^eEBVA, EBVB, HSV-1, and HHV7.

^fTwo EBVA and CMV, one EBVB and CMV, one HHV6 and CMV, one HSV-1 and CMV, and one HHV7 and CMV.

^gThree samples also submitted for HSV analysis.

^hThree HSV-1 and HHV6, one HHV6 and VZV, one HSV-1 and VZV, and one EBV and HHV7.

ⁱEBV and HHV6.

^jNot clinically diagnosed

^kOne HHV8 and CMV and one HHV8 and EBVA.