TABLE 2.
Comparison of malachite green microtube assay results with proportional method results (60 stock cultures)
| Druga | No. of strains with the following resultb:
|
% Agreement in isolated strains | Sensitivity (%)c | Specificity (%)d | |||
|---|---|---|---|---|---|---|---|
| Susceptible by both | Resistant by both | Resistant by MG, sensitive by LJ | Sensitive by MG, resistant by LJ | ||||
| SM | 25 | 29 | 3 | 4 | 90 | 87 | 89 |
| INH | 30 | 30 | 0 | 0 | 100 | 100 | 100 |
| RF | 30 | 30 | 0 | 0 | 100 | 100 | 100 |
| ETB | 24 | 28 | 5 | 3 | 86 | 90 | 82 |
| CIP | 53 | 7 | 0 | 0 | 100 | 100 | 100 |
| DC | 55 | 3 | 1 | 1 | 96 | 75 | 98 |
| OF | 53 | 3 | 3 | 93 | 75 | 94 | |
| CAP | 55 | 3 | 1 | 1 | 96.6 | 75 | 98 |
| ETH | 49 | 3 | 6 | 2 | 86 | 60 | 89 |
| PAZ | 55 | 3 | 1 | 1 | 96 | 75 | 98 |
| KAN | 54 | 4 | 1 | 1 | 96 | 80 | 98 |
| AM | 51 | 3 | 3 | 3 | 90 | 50 | 94 |
a
Abbreviations: AM, ampicillin; CAP, caperomycin; CIP, ciprofloxacin; DC, doxycycline; ETB, ethambutol; ETH, erythromycin; INH, isonizid; KAN, kanamycin;OF, ofloxacin; PAZ, pyrazinamide; RF, rifampin; SM, streptomycin.
b
MG, malachite green microtube susceptibility assay; LJ, Löwenstein-Jensen culture medium.
c
The average sensitivity for all drugs studied was 80.5%.
d
The average specificy for all drugs studied was 95%.