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. 2007 Dec 12;46(2):689–699. doi: 10.1128/JCM.01821-07

TABLE 2.

Spoligotypes, nucleotide changes in drug resistance genes and ogt codon 15, and phenotypic drug resistance profiles as determined by drug susceptibility testing of selected clinical strains from Brazila

Strain INH resistance profile Change in katG sequence Change in inhA sequence RIF resistance profile Change in rpoB sequence EMB resistance profile Change in ogt codon 15 sequence Spoligotypeb
1 R — — — — — ACC15AGC Haarlem3
2 R — — — — — wt X2
3 R — — — — — wt LAM6
4 R — — — — — ACC15AGC Haarlem1
5 R — — — — — ACC15AGC Haarlem3
6 R — — — — — ACC15AGC Haarlem3
7 R — — — — — wt Beijing
8 R — — — — — wt LAM9
9 R — — — — — ACC15AGC Haarlem3
10 R — — — — — ACC15AGC Haarlem3
11 R — — — — — wt S
12 R — — — — — ACC15AGC Haarlem3
13 R — — — — — ACC15AGC Haarlem3
14 R CTG300CCG C(−15)T — CAC526GAC — wt LAM4
15 R wt C(−15)T — TCG531TTG — wt T1
16 R wt C(−15)T — TCG531TTG — wt T1
17 R AGC315ACC wt R TCG531TGG R wt LAM2
18 R AGC315ACC wt R TCG531TTG — wt LAM3
19 R wt C(−15)T S wt R wt T1
20 R wt C(−15)T S wt S wt LAM9
21 R AGC315ACC wt R ACC525ACG, CAC526TCC, AAG527CAG S wt LAM9
22 R wt wt S wt S wt LAM4
23 R wt C(−15)T S wt S wt LAM2
24 R AGC315ACC C(−15)T — CAC526TCC — wt T1
25 R AGC315ACC C(−15)T — CAC526TAC — wt LAM1
26 R AGC315ACC wt R TCG531TTG — ACC15AGC Haarlem1
27 R AGC315ACC C(−15)T R CAC526TAC S wt LAM4
28 R wt wt R GAC516TAC R wt U
29 R AGC315ACC wt R GAC516GTC S wt LAM3/S
30 R AGC315ACC C(−15)T — CAC526TAC — — —
31 R AGC315ACC wt R CAC526CTC R — —
32 R AGC315ACC wt R TCG531TTG R — —
33 R AGC315ACC wt R TCG531TTG R — —
34 R wt wt R wt R — —
35 R AGC299GGC wt R TCG531TTG R — —
36 R wt wt S wt R — —
37 R wt wt — ATG515ATT, GAC516TAC — — —
38 R wt C(−15)T R TCG531TTG S — —
39 R wt C(−15)T — TCG531TTG — — —
40 R wt C(−15)T — TCG531TTG — — —
41 R AGC315ACC wt R GTC176TTC — — —
42 R AGC315ACC wt R GAC516GAG, TCG522TTG S — —
43 R wt wt R TCG531TTG R — —
44 R wt C(−15)T R TCG531TTG R — —
45 R AGC315ACC wt R TCG531TTG S — —
46 R AGC315ACC wt R CAC526GAC S — —
47 R AGC315ACC wt S wt R — —
a

R, resistant; S, susceptible; —, not determined or data not available; wt, wild type.

b

See reference 6.