TABLE 6.
Results of MLPA for drug-resistant clinical M. tuberculosis isolates from Brazila
| Strain | MLPA result obtained with probe:
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| embB-306 | katG-315 | inhA-15 | 16S rRNA | rpoB-176 | rpoB-531 | rpoB-526G | rpoB-526T | rpoB-522 | IS6110 | katG-463 | gyrA-95 | mutT2-58 | ogt-12 | ogt-15 | ogt-37 | TbD1 | |
| 1 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 2 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 3 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 4 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 5 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||
| 6 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 7 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 8 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 9 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 10 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||
| 11 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 12 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 13 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 14 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 15 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 16 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 17 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 18 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 19 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 20 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 21 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 22 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 23 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 24 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 25 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 26 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||
| 27 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||
| 28 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 29 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 30 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||
| 31 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 32 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 33 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 34 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 35 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 36 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 37 | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||||
| 38 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 39 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 40 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 41 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 42 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 43 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
| 44 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 45 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 46 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | ||||||||||
| 47 | ▪ | ▪ | ▪ | ▪ | ▪ | ▪ | |||||||||||
▪, a product was obtained for the targeted SNP or region. Where there is no symbol, no product was detected. Genotyping data and data on phenotypic and genotypic drug resistance are given in Table 2.