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. 2007 Dec 5;46(2):652–664. doi: 10.1128/JCM.01574-07

FIG. 1.

FIG. 1.

UPGMA dendrogram based on concatenated sequences from the MLST scheme C loci CdAAT1a, CdACC1, CdADP1, CdMPIb, CdSYA1, exCdVPS13, exCdZWF1b, CdRPN2, CdGLN4, and CdAAT1b (Table 3), showing percentages of sequence homology for 50 C. dubliniensis isolates from a broad range of geographical locations, including isolates from all known ITS genotypes (Table 1). Three distinct major clades termed clades C1 to C3 are evident at 99.69% sequence homology. C1 consists of ITS genotype 1 isolates exclusively, C2 consists of ITS genotype 2 isolates exclusively, and C3 consists of ITS genotype 3 and 4 isolates. Twenty-three of the 50 isolates included in the study were previously fingerprinted with the C. dubliniensis-specific probe Cd25 (4, 21), and the Cd25 fingerprint groups of these isolates are indicated by shaded rectangular boxes.