FIG. 12.
Model of the nitrogen regulation network in F. fujikuroi. MepB is postulated as a key component in this model, acting as the major ammonium permease. In addition, mepB might also act as a nitrogen sensor either by mediating the signal of nitrogen availability or indirectly by causing a drop in the intracellular glutamine level. In the latter case we suggest an intracellular sensor transducing the glutamine signal to AreA via TOR and/or additional signaling pathways. WT, wild type.