TABLE 2.

Transcripts showing statistically significant twofold or greater differential accumulation between mutant and wild type at multiple time points

Type of change in transcript abundance and transcript identifiera	Transcript abundance in the mutant relative to wild type at the indicated time pointb						Annotation
	0 h	P0 h	96 h	P96 h	144 h	P144 h
Twofold or greater increase between wild type and mutant at all time points: fgd246-110_at	4.252137	1.70E-07	2.961257	0.0003721	4.35791	5.88E-07	Hypothetical protein
Twofold or greater decrease between wild type and mutant at all time points
fg06105_s_at	−1.667428	3.26E-05	−1.544056	0.00103707	−1.81548	4.83E-06	Probable trimethyllysine dioxygenase
fgd361-40_s_at	−2.310062	7.23E-06	−2.286179	0.00069665	−1.875791	5.85E-06	Conserved hypothetical protein
Increase at 0 h and 96 h*
fgd318-850_at	4.205249	5.17E-06	1.885949	0.00306174	−0.775595	0.308734	Conserved hypothetical protein
fgd185-60_at	3.210368	1.31E-06	2.112676	0.00275112	−0.015636	0.975858	Conserved hypothetical protein
fgd197-120_at	2.983299	2.00E-05	3.231011	0.00374232	−0.789604	0.072781	Hypothetical protein
fgd21-20_at	2.585006	1.33E-05	3.126629	0.000714	−0.521372	0.301871	Hypothetical protein
fgd158-490_at	2.584465	3.26E-09	3.758745	0.00031145	−0.09127	0.742611	Probable pectin lyase precursor
fgd233-360_s_at	2.518178	2.38E-05	2.804031	0.00354073	−0.346337	0.20056	Hypothetical protein
fg09187_s_at	2.208471	2.86E-05	1.88661	0.00203256	−0.636026	0.107265	Related to VerA protein
fgd160-740_at	2.162682	4.44E-08	2.443102	7.39E-05	0.166141	0.547707	Conserved hypothetical protein
fg07734_at	1.818964	2.82E-05	3.329558	0.00023151	1.547734	0.004251	Related to global transactivator
Increase at 0 h and decrease at 96 h*
fgd292-290_x_at	4.260392	4.53E-10	−1.659034	0.00190987	0.348952	0.033907	Putative protein (EST hit)
fgd458-640_at	3.146793	3.02E-07	−1.276051	0.00170183	−0.482921	0.101694	Related to putative tartrate transporter
fgd4-40_at	3.124855	7.92E-06	−1.618002	0.00441397	−0.065222	0.833894	TOX1; related to KP4 killer toxin
fg12249_at	2.651301	9.82E-06	−1.947163	0.00309896	0.067724	0.859242	Probable amino acid transport protein GAP1
fg07325_s_at	2.186069	3.70E-05	−1.067731	0.00077608	−1.441705	0.003597	Related to ATP-binding cassette transporter protein YOR1
fgd320-650_at	1.260561	3.12E-07	−1.959269	0.00170962	−0.004734	0.979366	Hypothetical protein
Decrease at 0 h and increase at 96 h*
fgd199-110_s_at	−1.122248	3.28E-05	2.398922	0.00446521	0.085527	0.791343	Hypothetical protein
fgd112-310_at	−1.911777	8.49E-06	1.598495	0.00482901	2.132243	0.000159	Related to ARG8, acetylornithine aminotransferase
fgd266-180_at	−1.930477	2.96E-08	1.938448	0.00304904	−0.034996	0.915222	Conserved hypothetical protein
fgd425-330_at	−2.12576	1.26E-05	2.153474	0.0028155	−1.021158	0.028486	Related to ANON-37CS protein
fgd77-70_at	−2.285935	5.13E-06	3.955246	0.00321478	−0.319272	0.191412	Probable regulatory subunit of protein phosphatase-1
fgd148-1240_at	−2.324533	2.33E-05	2.198154	0.00390104	−0.61492	0.135032	Conserved hypothetical protein
fg04626_s_at	−2.640947	3.24E-05	3.575254	0.00025086	−0.026996	0.935111	Hypothetical protein
Decrease at 0 h and 96 h*
fg01182_s_at	−1.213758	6.88E-06	−1.160318	0.00016456	−1.044243	0.000145	Conserved hypothetical protein
fg06960_s_at	−1.36357	4.90E-06	−1.061768	0.00012174	−1.312393	0.00465	Related to Ku70-binding protein
fgd56-90_at	−1.384284	2.98E-06	−2.039921	0.00023909	0.357408	0.189783	Probable multiubiquitin chain binding protein (MBP1)
fgd450-20_at	−1.398908	1.96E-05	−1.399369	0.00086921	−0.564188	0.330237	Probable phosphatidylinositol/phosphatidylcholine transfer protein SEC14
fgd104-290_at	−1.432652	6.95E-06	−1.847161	0.0029308	−2.325124	0.000334	Conserved hypothetical protein
fgd422-230_at	−1.54976	3.70E-06	−1.312596	0.00028198	−1.461646	0.034723	Probable coatomer epsilon subunit
fg00331_s_at	−1.584002	3.51E-05	−2.637301	0.00105877	0.20298	0.541548	putative protein (EST hit)
fgd35-590_at	−1.626283	4.53E-06	−2.011254	0.00309951	−1.186748	0.001245	Probable septum formation maf
fg00430_s_at	−1.753789	2.95E-05	−1.739395	0.00224068	−1.538549	0.000397	Probable oligosaccharyltransferase
fg08308_s_at	−1.83793	3.73E-06	−1.467145	0.00483457	0.147557	0.543416	ABC2; related to multidrug resistance protein
fgd383-190_at	−1.997796	2.90E-07	−1.792443	0.00110624	−0.905406	0.005111	Conserved hypothetical protein
fgd24-30_at	−2.028044	1.84E-05	−1.579857	0.00059991	−1.650269	0.000555	Conserved hypothetical protein
fgd248-140_at	−2.053918	2.44E-05	−1.838453	0.00458005	−1.713851	0.001132	Probable aldo-keto reductase YPR1
fgd104-420_at	−2.108565	7.59E-06	−1.449971	0.00035639	−0.236224	0.159022	Probable branched-chain alpha-ketoacid dehydrogenase kinase; mitochondrial precursor
fgd168-1760_s_at	−2.108666	5.61E-09	−1.108928	0.00270452	-1.463851	0.054713	Related to type 2C protein phosphatase
fgd335-320_at	−2.145885	1.17E-06	−1.382001	0.00043239	2.014346	0.010176	Probable glycine decarboxylase P subunit
fgd367-120_at	−2.170614	6.10E-08	−1.815004	0.00365397	1.029645	0.009561	Related to n-carbamoyl-l-amino acid hydrolase
fgd59-140_at	−2.553609	3.19E-06	−1.51113	0.00069322	−0.825075	0.009643	Probable GTPase-activating protein of the rho/rac family (LRG1 protein)
fgd212-830_at	−2.58426	5.02E-07	−1.522224	0.0020098	−1.344456	0.098771	Probable 3-hydroxyisobutyrate dehydrogenase
fgd170-50_s_at	−2.753081	1.54E-06	−1.113897	0.00290648	−0.848131	0.000775	Probable potassium transporter TRK-1
fgd192-1180_at	−3.780183	2.01E-08	−1.404931	0.00321436	0.313153	0.495277	Related to serine-type carboxypeptidase F precursor
fgd90-10_at	−4.045339	2.81E-05	−1.489611	0.00080104	−3.030282	0.001579	Probable DIP5-glutamate and aspartate permease; able to mediate transport of other amino acids

^aSignificant changes in abundance in the mutant are indicated by an asterisk.

^bLog 2 relative change. Negative numbers and positive numbers represent a decrease and increase, respectively, in mutant transcript abundance compared with wild type. P values are identified by time point (e.g., P value for change in transcript abundance at 0 h is P_{o h}). The cutoffs for statistical significance vary between treatments.