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. Author manuscript; available in PMC: 2008 Oct 26.
Published in final edited form as: J Mol Biol. 2007 Aug 14;373(3):587–598. doi: 10.1016/j.jmb.2007.07.066

Figure 5.

Figure 5

The fractional occupancy of the three states of the TnC-F1 and TnC-F2 containing thin filaments as a function of calcium concentration. The occupancy at pCa 8.9 and pCa 4.5 are based on the values of KB and KT given in Table 1. (Calculated from fraction of actin as C states = 1/(1 + KT+1/KB), then B states = C states/KB and M states = C states KT). The values of KB at pCa 7 and 6 are based on the pCa plots of Figure 3(c) and were 0.37 and 1.4 for TnC-F1 and 1.03 and 9.5 for TnC-F2, respectively. KT was independent of calcium for TnC-F2 while for TnC-F1 it had a small dependence on calcium and was assumed to follow the same pCa dependence as KB with values of 0.55 at pCa 7 and 0.68 at pCa 6. Values for the rabbit TnC are not shown but were very similar to those for TnC-F2.