Table 2.
HLA-A*02 and subtype A*0206 proviral loads in HCs
| HLA subtype | HAM/TSP
|
HCs
|
||||
|---|---|---|---|---|---|---|
| Median proviral load | No. of subjects | P | Median proviral load | No. of subjects | P | |
| A*02+ | 524.8 | 67 | 0.18 | 16.8 | 100 | 0.014 |
| A*02− | 616.6 | 155 | 50.1 | 101 | ||
| A*0206+ | 631.0 | 28 | 0.42 | 10.5 | 52 | 0.004 |
| A*0206− | 562.3 | 194 | 43.7 | 149 | ||
| A*02+ A*0206− | 426.6 | 39 | 0.026 | 38.9 | 48 | 0.40 |
| A*02− | 616.6 | 155 | 50.1 | 101 | ||
HLA-A*02 and subtype A*0206 were associated with a reduced provirus load in HCs. Other A*02 subtypes were associated with a reduced provirus load in HAM/TSP patients.
Median proviral load given as proviral copy number per 104 PBMC. P reported as two-tailed, uncorrected Mann–Whitney U test.