Table 4.
HAM/TSP
|
HCs
|
|||||
---|---|---|---|---|---|---|
Median proviral load | No. of subjects | P | Median proviral load | No. of subjects | P | |
DRB1*0101+ | 331.1 | 34 | 0.024 | 49.0 | 20 | 0.33 |
DRB1*0101− | 602.6 | 161 | 34.7 | 163 | ||
A*02− DRB1+ | 338.8 | 27 | 0.03 | 109.6 | 10 | 0.22 |
A*02− DRB1− | 631.0 | 107 | 41.7 | 83 | ||
A*02+ DRB1+ | 331.1 | 7 | 0.41 | 21.9 | 10 | 0.81 |
A*02+ DRB1− | 524.8 | 54 | 21.9 | 80 |
A significant reduction in provirus load is observed in the HAM/TSP patients, but not in the A*02+ patients or in the HCs.
Proviral copy reported as number per 104 PBMC. P level reported using two-tailed Mann–Whitney U test.