Table 1.
Sample phenotypic distributions
| Name Phenotype | Sample 1 Obesity | Sample 2 Obesity replication | Sample 3a Fat cells | ||
| Obese | Women (N = 581) | Men (N = 124) | Women (N = 689) | Men (N = 148) | Women (N = 216) |
| Age (years) | 41 ± 12 | 45 ± 13 | 43 ± 11 | 45 ± 12 | 38 ± 10 |
| BMI (kg/m2) | 43 ± 5 | 45 ± 5 | 37 ± 5 | 45 ± 5 | 38 ± 5 |
| HOMAIR | 5.3 ± 5.7 | 10.5 ± 16.5 | 4.5 ± 5.7 | 8.2 ± 5.5 | 3.8 ± 2.8 |
| Pl-cholesterol (mmol/l) | 5.2 ± 1. | 5.2 ± 1.2 | 5.3 ± 1.1 | 5.2 ± 1.1 | 5.2 ± 1.1 |
| Pl-HDL cholesterol (mmol/l) | 1.2 ± 0.3 | 1.0 ± 0.2 | 1.3 ± 0.3 | 1.1 ± 0.3 | 1.2 ± 0.3 |
| Pl-triglycerides (mmol/l) | 1.7 ± 0.9 | 2.3 ± 2.3 | 1.7 ± 1.0 | 2.0 ± 1.2 | 1.6 ± 1.0 |
| Lean | Women (N = 338) | Men (N = 64) | Women (N = 525) | Men (N = 88) | Women (N = 12) |
| Age (years) | 50 ± 4 | 57 ± 8 | 39 ± 6 | 36 ± 11 | 33 ± 8 |
| BMI (kg/m2) | 22 ± 2 | 23 ± 2 | 22 ± 3 | 23 ± 1 | 22 ± 2 |
| HOMAIR | 1.3 ± 0.7 | 1.6 ± 0.8 | 1.3 ± 1.0 | 1.4 ± 0.7 | 1.4 ± 0.9 |
| Pl-cholesterol (mmol/l) | 5.4 ± 1.0 | 5.7 ± 1.1 | 4.7 ± 0.8 | 4.9 ± 1.1 | 4.8 ± 0.7 |
| Pl-HDL cholesterol (mmol/l) | 1.7 ± 0.4 | 1.4 ± 0.4 | 1.6 ± 0.4 | 1.3 ± 0.5 | 1.6 ± 0.4 |
| Pl-triglycerides (mmol/l) | 0.9 ± 0.5 | 1.5 ± 1.0 | 0.9 ± 0.5 | 1.3 ± 1.4 | 0.8 ± 0.2 |
Values are mean ± SD
a) 99 subjects overlap between sample 1 and 3.