Table 3.

Association of ESR1 and ESR2 haplotypes with obesity

		Cases		Controls
Haploblock	%	Specific haplotype (n)	Other (n)	Specific haplotype (n)	Other (n)	P value
ESR1
rs488133-rs532010-rs11155813
CGT	34	449	917	288	508	0.12
TAT	33	455	911	250	546	0.37
CAT	21	285	1081	167	629	0.96
CAC	11	158	1208	82	714	0.36
rs1709182
T	67	925	441	516	282	0.14
C	33	441	925	282	516	0.14
rs6557170-rs2347867
GA	68	916	450	549	249	0.40
AG	21	299	1067	165	633	0.52
GG	11	151	1215	84	714	0.68
rs12154178
A	18	976	390	575	223	0.76
C	28	390	976	223	575	0.76
rs3020317
T	82	1116	250	652	146	1.00
C	18	250	1116	146	652	1.00
rs1884054
A	67	920	446	531	267	0.70
C	33	446	920	267	531	0.70
rs7754762-rs7757956-rs9340954-rs3020368
TTTC	69	947	420	557	239	0.75
ATGC	13	185	1181	99	697	0.47
TAGT	8	113	1253	69	727	0.77
TAGC	5	67	1299	43	753	0.59
rs3778082-rs2982896
GC	63	862	502	502	296	0.90
GT	23	310	1054	197	601	0.30
AC	14	192	1172	99	699	0.27
rs2813544-rs1543403
AC	48	640	727	396	402	0.21
AG	31	419	948	248	550	0.82
GG	21	301	1065	152	646	0.10
ESR2
rs3020450-rs1271572-rs1887994-rs7159462
CACC	46	639	727	346	452	0.12
TCCC	29	372	994	254	544	0.024*
CCAC	11	153	1213	79	719	0.33
CCCT	8	116	1251	65	733	0.83
CCCC	6	81	1285	49	749	0.86
rs1256061-rs1256063
TG	50	671	689	401	397	0.68
GG	41	547	814	331	467	0.57
GA	10	142	1218	66	732	0.10
rs4986938-rs928554-rs1152582
GGG	44	619	747	333	465	0.10
AAC	38	502	864	310	488	0.32
GAC	18	233	1133	149	649	0.35