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. 2007 Oct 27;36(Database issue):D623–D631. doi: 10.1093/nar/gkm900

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — The regulatory overview. The diagram is composed of three nested ellipses. The innermost ellipse comprises genes that are regulating other genes, but that are not regulated by any genes. The middle ellipse comprises genes that are both regulators and regulatees (= regulated by some entity), and the outermost ellipse comprises genes that are regulated, but do not regulate. The triangles that extend outward from the outer ellipse are collections of many genes that share the same set of regulator genes-although genes within a triangle may respond to those regulators in different ways. They are drawn within triangles simply to keep the size of the outer ellipse manageable.