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. 2007 Oct 26;36(Database issue):D497–D503. doi: 10.1093/nar/gkm905

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Protein sequence alignment. The PB2 (A) and NS1 (B) protein sequences from all 10 influenza A virus H5N1 duck sequences isolated in China during 2001 were aligned separately using the BioHealthBase implementation of the MUSCLE algorithm. Only the PB2 protein region from aa661 to aa759 and the NS1 protein region from aa1 to aa120 are shown. The key N701D substitution found to affect virulence in DkXi35 PB2 and the G66E difference between DkXi22 and DkXi35 in the NS1 RNA-binding domain are highlighted.