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. Author manuscript; available in PMC: 2008 Feb 12.
Published in final edited form as: J Immunol. 1998 Nov 1;161(9):4563–4571.

FIGURE 2.

FIGURE 2

β-gal-specific production of IgG1 and IgG2a in vaccinated mice infected with β-gal DNA plus IL-12 DNA or CD40LT DNA. Mice were vaccinated in a similar manner to that described in Figure 1. In some groups, mice were treated with anti-IL-12 (1 mg) at the time of each vaccination. Pooled sera (n = 4–6 mice per group) were collected 2 to 3 wk after the second immunization and tested for β-gal-specific Ab IgG2a (A) or IgG1 (B). Data shown are an average of duplicate absorbance (OD) values using serial fivefold dilutions with SEM. Results are representative of five independent experiments. *, p < 0.05 in comparing IgG1/IgG2a produced from mice vaccinated with β-gal plus CD40LT DNA with that from mice vaccinated with β-gal DNA alone.