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. Author manuscript; available in PMC: 2008 Feb 12.
Published in final edited form as: J Immunol. 1998 Nov 1;161(9):4563–4571.

FIGURE 7.

FIGURE 7

Cytokine or CD40LT DNA induces protective immunity to mice infected with L. major. BALB/c mice (n = 7 per group) were initially immunized and boosted 2 wk later with SLA (leishmanial protein) plus control DNA, IL-12 DNA, CD40LT DNA, or rIL-12 (2 μg). Two weeks after the boost, mice were challenged in the hind footpad with 1 × 105 live L. major metacyclic promastigotes. Weekly footpad measurements represent the average footpad scores ± SEM. Results are representative of two independent experiments.