Figure 5.

Transepithelial transport of ^99mTc-sestamibi and [³H]Taxol across confluent monolayers of rat CP epithelial cells, wherein drug is added to either the basal (Aa, Ba, and Ca) or the apical (Ab, Bb, and Cb) side of the monolayers. (A) ^99mTc-sestamibi added in the absence and presence of GF120918 (300 nM). (B) ^99mTc-sestamibi added in the absence and presence of MK-571 (100 μM). (C) [³H]Taxol added in the absence and presence of GF120918 (300 nM). Each point represents the mean value of three monolayers; bars represent ±SEM when larger than the symbol.