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. Author manuscript; available in PMC: 2009 Jan 23.
Published in final edited form as: Brain Res. 2007 Nov 19;1190:78–85. doi: 10.1016/j.brainres.2007.11.017

Figure 4. RGS9 KO Mice Exhibit Normal Anxiety-like Behavior, Pre-Pulse Inhibition and Startle Amplitude.

Figure 4

(A) Both context- and cue-dependent fear learning was normal in RGS9 KO mice (context: RGS9 KO vs. WT, p = 0.52, cue: RGS9 KO vs. WT, p = 0.90). Legend in A applies to Panels A-D. (B) Anxiety-like behavior in the RGS9 KO mice does not differ from wt as measured by time spent in the center of an open field (p = 0.372). (C) In a pre-pulse inhibition test, RGS9 KO mice showed normal sensorimotor gating (4db, p = 0.49; 8db, p = 0.12; 16db, p =0.97). (D) Finally, startle amplitude did not differ across genotype (p = 0.65).