Table 1.
Cellular/Extracellular Concentration Ratios Observed in Resting Human Polymorphonuclear Leukocytes
| Extracellular Concentration (μg/ml) | Cellular/Extracellular for Minocycline | Cellular/Extracellular for Doxycycline | Cellular/Extracellular for Tetracycline |
|---|---|---|---|
| 2 | 84.7 ± 8.9 | 8.06 ± 5.60 | 14.0 ± 1.4* |
| 5 | 65.5 ± 3.9 | 6.39 ± 1.46 | 5.49 ± 0.69 |
| 10 | 64.2 ± 6.7 | 7.55 ± 1.24 | 1.81 ± 0.49 |
| 20 | 60.6 ± 6.6 | 9.84 ± 1.34 | 2.72 ± 0.61 |
Results are expressed as the mean of four determinations ± SEM. Within each column, the differences in the mean values are greater than would be expected by chance (P <0.05; ANOVA).
*
Values that are significantly different from other means in the same column (P <0.05; Tukey test).