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. Author manuscript; available in PMC: 2008 Feb 13.
Published in final edited form as: J Dent Res. 2005 Apr;84(4):320–323. doi: 10.1177/154405910508400405

Figure 2.

Figure 2

Effects of TGF-β1 and TNF-α on fibroblast minocycline accumulation. Experiments were conducted as described in the legend for Fig. 1. The data represent the mean ± SEM of 5 individual experiments. There were no significant effects by TGF at 1 hr (P = 0.24, repeated-measures ANOVA). However, incubation with TGF for 6 hrs produced a significant treatment effect (P < 0.001, repeated-measures ANOVA), and TNF-α produced a significant treatment effect at 1 and 6 hrs (P < 0.001 and P ≤ 0.008, respectively). Conditions that produced a significant increase in minocycline accumulation compared with controls (P > 0.05, Dunnett’s test) are indicated by *.