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Pressure induces a smaller depolarization in cav-1−/− arteries. A: original membrane potential recordings in pressurized (10 and 50 mmHg) cav-1+/+ and cav-1−/− arteries. B: regulation of arterial wall membrane potential by intravascular pressure in cav-1+/+ (10 mmHg, n = 6, 50 mmHg, n = 14) and cav-1−/− (10 mmHg, n = 7, 50 mmHg, n = 14) arteries. *P < 0.05 when compared with membrane potential at 10 mmHg; #P < 0.05 when compared with membrane potential of cav-1+/+ arteries at 50 mmHg.
