Table IV.
Activation energies for dissociation of the native gp100209 peptide and the T2M-modified variant from HLA-A2a
ΔH‡ | ΔS‡ | ΔΔH‡ | ΔΔS‡ | |
---|---|---|---|---|
Native | 25.4 ± 2.4 | 3.3 ± 0.5 | −6.2 ± 3.5b | −22.7 ± 5.8b |
T2M-mod | 19.3 ± 2.5 | −19.4 ± 5.8 |
Enthalpies in kilocalories per mole; entropies in calories per mole per K.
Values for the native peptide subtracted from the values for the T2M-modified variant