Table 1.
Model | P | likelihood | Parameters estimated | Positively selected sites |
---|---|---|---|---|
Branch Models | ||||
1ω | 1 | -1431.66 | ω all branches = 0.048 | N/A |
2ω | 2 | -1431.41 | ω placental mammals = 0.054; background = 0.04 | N/A |
3ω | 3 | -1408.70 | ω anthropoid = 0.431; ω other placentals = 0.008; ω background = 0.042 | N/A |
Free Ratio | 55 | -1388.00 | ω estimated independently for each branch (see Fig. 1) | N/A |
Branch-site models | ||||
Model A | 4 | -1399.23 | p0 = 0.90; p1 = 0.012; p(2a+2b) = 0.085; ω0 = 0.021; ω1 = 1; background ω2a = 0.021; ω2b = 1; foreground, ω2a = ω2b = 4.61 | 5 (1.00); 38 (0.99); 41 (0.53); 64 (1.00); 70 (0.97) |
Model A (omega fixed) | 3 | -1403.73 | p0 = 0.80; p1 = 0.011; p(2a+2b) = 0.192; ω0 = 0.02; ω1 = 1; background ω2a = 0.02; ω2b = 1; foreground, ω2a = ω2b = 1 | Not allowed |
P, number of parameters. Numbers in parentheses represent the posterior probability of each amino acid listed to be in the class of sites under positive selection.