Table 2.

Genotype distribution and allele frequency of the G1522A variant in the SMPD1 gene in control and low HDL-cholesterol subjects.

Genotype or allele	Control subjects (n)	Low HDL-cholesterol subjects (n)	χ2, two-sided p-value and O.R.
GG	56.1% (129)	64.1% (75)	0.152†
AG	38.3% (88)	29.1% (34)	0.72 (0.45–1.13)‡
AA	5.6% (13)	6.8% (8)
G	75.2%	78.6%	0.317
A	24.8%	21.4%	0.82 (0.57–1.20)‡

O.R., odd ratio

^† AG and AA genotypes where pooled for statistical analysis

^‡ 95% confidence interval for O.R.