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. 2007 Nov 26;153(3):497–507. doi: 10.1038/sj.bjp.0707600

Figure 1.

Figure 1

Relaxations of porcine coronary arteries to NTG (left panel) and DETA NONOate (right panel) following 24h incubation with NTG. Vessels were constricted with U46619 (10−7 to 3 × 10−7 M) before testing their relaxant responses. Data are shown as means±s.e.mean; n=7–10 for each group. *Significantly different from vessels incubated with NTG from 10−7 to 10−5 M (left panel) or with NTG at 10−6 and 10−5 M (right panel) (P<0.05); †significantly different from vessels incubated with NTG at 10−7 and 10−6 M (P<0.05). DETA NONOate, [2,2′-(hydroxynitrosohydrazono) bis(ethanamine)]; NTG, nitroglycerine; U46619, (9,11)-dideoxy-(11α,9α)-epoxymethanoprostaglandin F2α.