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. 2007 Nov 26;153(3):598–608. doi: 10.1038/sj.bjp.0707597

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Copyright 2008, Nature Publishing Group

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Comparison of chemical structures for eupalmerin acetate (EPA) and allopregnanolone. In all four figures, EPA is shown in grey with oxygens in red, whereas the allopregnanolone is shown in yellow. Hydrogens are removed from both molecules to provide a clearer view of the superposition. (a) A side view of the best superposition of EPA onto allopregnanolone matching the γ-lactone carbonyl to the C3 hydroxyl. (b) A top-down view of the same alignment. (c) A side view of EPA aligned with the C17 ketone. (d) A top-down view of this superposition.