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. 2007 Nov 26;153(3):528–535. doi: 10.1038/sj.bjp.0707586

Figure 3.

Figure 3

Effects of cys-LT1 receptor antagonists on the responses to indomethacin, aspirin and LTD4. The data are mean±s.e.mean of the number of EPO+ cells in liquid cultures established from BALB/c bone marrow, in the presence of IL-5 alone, or associated with the following: LTD4 (10−8 M), indomethacin (10−7 M) or aspirin (10−8 M), in the absence or in the presence of MK571 (a), 10−7 M, or montelukast (Mkt; b and c), at the indicated concentrations. Data are derived from 3 to 5 experiments. *P<0.05 relative to IL-5 controls. **P<0.05 relative to positive controls without MK571 or Mkt. cys-LT, cysteinyl-leukotriene; EPO, eosinophil peroxidase; IL, interleukin.